The general rule of thumb I would say is that the less you put in front of the lens the better. In theory and in a world of perfect glass (or very expensive glass) I don't think that combining the filters would reduce quality. Glass though is generally less than perfect so the less the better i recon.
Another thing to consider is that if you have a wide angle lens (which i know you do) it may start to show vignetting caused by the 15mm or so of extra barrel you have added by combining filters. I know that on my 16mm lens I have to have special "low profile" filters so that vignetting is not a problem (my hoya pro 77mm low profile circular polariser cost me £110

OUCH.)
You should also think about buying protector filters rather than uv's. But that's a whole nother story.....